Fludarabine – VJRegenMed https://mirror.vjregenmed.com The Video Journal of Regenerative Medicine Thu, 26 Aug 2021 17:40:28 +0000 en-US hourly 1 https://wordpress.org/?v=6.5.2 https://d2xz56kaqxj8if.cloudfront.net/wp-content/uploads/2023/09/12102509/VJR-Favicon.png Fludarabine – VJRegenMed https://mirror.vjregenmed.com 32 32 Novel strategies to optimize CAR T-cell therapy https://mirror.vjregenmed.com/video/sisc-m4mu3q-novel-strategies-to-optimize-car-t-cell-therapy/ Fri, 26 Feb 2021 14:08:27 +0000 http://13.40.107.223/video/sisc-m4mu3q-novel-strategies-to-optimize-car-t-cell-therapy/ Arnon Nagler, MD, Chaim Sheba Medical Center, Tel-Aviv, Israel, discusses approaches to optimize CAR T-cell therapy. CAR T-cell therapies have achieved impressive outcomes in hematological malignancies. However, setbacks such as limited CAR T-cell persistence after infusion, high relapse rates, resistance, and toxicities continue to be experienced. Prof. Nagler outlines novel strategies to improve CAR T-cell function, including novel constructs, new targets, bispecific CAR-T cells, and allogeneic CAR-Ts. This interview took place during the 3rd European CAR T-cell Meeting.

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