Anne des Rieux – VJRegenMed

Spinal cord regeneration with dental stem cells

Simon Ng — Wed, 05 Jan 2022 17:32:25 +0000

Anne des Rieux, PhD, Université catholique de Louvain, Louvain, Belgium, provides an overview of using dental stem cells to treat spinal cord injuries. In vivo and in vitro studies in mouse models have demonstrated promising results and additional research is currently being undertaken to assess how stem cells react to inflammatory stimuli, as well as genomic changes post-implant. This interview took place at the 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS 2021).

The role of stem cells in treating CNS disorders

Simon Ng — Wed, 05 Jan 2022 17:32:23 +0000

Whilst stem cells such as mesenchymal stem cells have proven to be safe in clinical trials, various issues need to be addressed to successfully develop cellular therapies for central nervous system (CNS) diseases. Anne des Rieux, PhD, Université catholique de Louvain, Louvain, Belgium, describes various barriers associated with using stem cells in CNS diseases. Large scale manufacturing of stems cells remain limited, due to logistical constraints and cell contamination. Dr des Rieux additionally highlights the need to improve delivery systems and the advantages of using allogeneic cells. This interview took place at the 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS 2021).

Delivering drugs to the CNS with extracellular vesicles

Simon Ng — Wed, 05 Jan 2022 17:32:21 +0000

Anne des Rieux, PhD, Université catholique de Louvain, Louvain, Belgium, discusses promising research within extracellular vesicles (EVs) for the treatment of central nervous system (CNS) diseases. Whilst EVs have been previously been investigated as diagnostic tools, current research suggests EVs can play a role in drug delivery. EVs, which contain various lipids, proteins and mRNA, can cross the blood-brain barrier, which is advantageous for the delivery of drugs to the brain. This interview took place at the 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS 2021).