Frank Marini – VJRegenMed https://mirror.vjregenmed.com The Video Journal of Regenerative Medicine Wed, 25 Aug 2021 11:21:46 +0000 en-US hourly 1 https://wordpress.org/?v=6.5.2 https://d2xz56kaqxj8if.cloudfront.net/wp-content/uploads/2023/09/12102509/VJR-Favicon.png Frank Marini – VJRegenMed https://mirror.vjregenmed.com 32 32 Imaging in regenerative medicine: current landscape and exciting technologies https://mirror.vjregenmed.com/video/dgwiam3umei-imaging-in-regenerative-medicine-current-landscape-and-exciting-technologies/ Thu, 12 Aug 2021 11:48:36 +0000 http://13.40.107.223/video/dgwiam3umei-imaging-in-regenerative-medicine-current-landscape-and-exciting-technologies/ Frank Marini, PhD, Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, provides an overview of imaging techniques used in regenerative medicine. Improvements in optical imaging have resulted in an improved understanding of spatial biology and novel high throughput technologies with improved resolution such as multiphoton microscopy, lattice light-sheet microscopy and optical coherence tomography provide non-invasive imaging methods for a wide range of biological processes, including tumor formation or the effects of chemotherapy at a cellular level. Improving our knowledge of cellular biology in a three-dimensional space will be necessary in making advances within regenerative medicine. This interview took place at the 2021 World Stem Cell Summit (WSCS).

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INCITE: a novel optical clearing technology for 3D imaging https://mirror.vjregenmed.com/video/f2pw-e2n2yq-incite-a-novel-optical-clearing-technology-for-3d-imaging/ Thu, 12 Aug 2021 11:48:34 +0000 http://13.40.107.223/video/f2pw-e2n2yq-incite-a-novel-optical-clearing-technology-for-3d-imaging/ Frank Marini, PhD, Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, provides an overview of index-matched clear imaging technology (INCITE). Animal tissues are made up of multiple components and the different refractive indices of each component makes tissues hard to view under a microscope. INCITE is optical clearing technology that utilizes propriety chemistry to fix animal tissues in a three-dimensional space, which is then run through a pressurized system to optically clear the tissue, making it transparent, thus homogenizing the refractive indices in the tissue. This technology offers the potential to improve the understanding of cellular interactions and spatial biology and could lead to the mapping of all cells in the human body to develop cell atlases. This interview took place at the 2021 World Stem Cell Summit (WSCS).

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