Kevin McNerney – VJRegenMed https://mirror.vjregenmed.com The Video Journal of Regenerative Medicine Thu, 09 Mar 2023 11:31:48 +0000 en-US hourly 1 https://wordpress.org/?v=6.5.2 https://d2xz56kaqxj8if.cloudfront.net/wp-content/uploads/2023/09/12102509/VJR-Favicon.png Kevin McNerney – VJRegenMed https://mirror.vjregenmed.com 32 32 Outcomes of children and young adults with B-ALL following tisa-cel reinfusion https://mirror.vjregenmed.com/video/s05upsl2goi-outcomes-of-children-and-young-adults-with-b-all-following-tisa-cel-reinfusion/ Thu, 09 Mar 2023 11:31:48 +0000 https://mirror.vjregenmed.com/video/s05upsl2goi-outcomes-of-children-and-young-adults-with-b-all-following-tisa-cel-reinfusion/ Kevin McNerney, MD, MSc, Johns Hopkins All Children’s Hospital, St. Petersburg, FL, shares the results of a retrospective study evaluating the safety and efficacy of tisagenlecleucel (tisa-cel) reinfusion in children and young adults with B-cell acute lymphoblastic leukemia (B-ALL). Overall, the study showed that second CAR-T infusions were well tolerated, allowed patients to achieve a complete remission (CR) or re-establish B-cell aplasia (BCA), and could be used as a bridge to transplant. However, most remissions were brief and BCA was limited. This interview took place at the 2023 Transplantation & Cellular Therapy Meetings of ASTCT™ and CIBMTR® held in Orlando, FL.

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