https://mirror.vjregenmed.com The Video Journal of Regenerative Medicine Mon, 15 Aug 2022 16:26:57 +0000 en-US hourly 1 https://wordpress.org/?v=6.5.2 https://d2xz56kaqxj8if.cloudfront.net/wp-content/uploads/2023/09/12102509/VJR-Favicon.png https://mirror.vjregenmed.com 32 32 https://mirror.vjregenmed.com/video/hg8gcrxo37y-advanced-cell-selection-for-the-manufacture-of-protrans-cell-therapy/ Wed, 20 Oct 2021 17:41:35 +0000 http://13.40.107.223/video/hg8gcrxo37y-advanced-cell-selection-for-the-manufacture-of-protrans-cell-therapy/ Mathias Svahn, PhD, MScEng, NextCell Pharma AB, Huddinge, Sweden, describes the cell selection and manufacturing process for ProTrans, an umbilical cord-derived mesenchymal stem cell (MSC)-based therapeutic currently being investigated for the treatment of type 1 diabetes. He discusses the use of potency assays and a proprietary selection algorithm to support the identification of optimal donors and the selection of cells with high potency and efficacy based on functionality, immune cell interaction and signaling. In addition, the use of pooled MSCs from multiple donors enhances reproducibility and cells are only cultured for three passages in order to preserve cell potency. This interview took place at the Advanced Therapies Congress & Expo 2021.

]]> https://mirror.vjregenmed.com/video/yktddu3n_no-the-benefits-of-umbilical-cord-derived-mscs-as-a-cell-source/ Wed, 13 Oct 2021 17:11:11 +0000 http://13.40.107.223/video/yktddu3n_no-the-benefits-of-umbilical-cord-derived-mscs-as-a-cell-source/ Mathias Svahn, PhD, MScEng, NextCell Pharma AB, Huddinge, Sweden, gives an overview of the use and benefits of umbilical cord (UC)-derived mesenchymal stem cell (MSC) as a cell source for cell-based therapeutics. Compared to bone marrow-derived MSCs, which have been under investigation in a range of autoimmune conditions and graft-versus-host disease for a number of years, UC-MSCs have more recently started being utilized and investigated. UC-MSCs constitute a young, potent and fast-growing source of cells that can be obtained from discarded tissue, thus reducing ethical implications. This interview took place at the Advanced Therapies Congress & Expo 2021.

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