Melvin Gurian – VJRegenMed https://mirror.vjregenmed.com The Video Journal of Regenerative Medicine Fri, 21 Jan 2022 11:15:00 +0000 en-US hourly 1 https://wordpress.org/?v=6.5.2 https://d2xz56kaqxj8if.cloudfront.net/wp-content/uploads/2023/09/12102509/VJR-Favicon.png Melvin Gurian – VJRegenMed https://mirror.vjregenmed.com 32 32 Determining the metabolic requirements for stem cell survival https://mirror.vjregenmed.com/video/1ig4tm_dpkm-determining-the-metabolic-requirements-for-stem-cell-survival/ Mon, 17 Jan 2022 13:05:32 +0000 http://13.40.107.223/video/1ig4tm_dpkm-determining-the-metabolic-requirements-for-stem-cell-survival/ Melvin Gurian, University of Twente, Enschede, The Netherlands, discusses identifying the minimum metabolic requirements for large scale growth of stem cells including mesenchymal stem cells. Uptake of oxygen and metabolites currently restrict clinical production of tissue engineered products and elucidating the optimal metabolic conditions for cells is essential for cell growth. Creation of a metabolic library of various sugars, amino acids and fatty acids can reveal which metabolites are necessary for cell survival. This interview took place at the 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS 2021).

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Enhancing in vivo cell growth with metabolites https://mirror.vjregenmed.com/video/gtirnaab8kc-enhancing-in-vivo-cell-growth-with-metabolites/ Mon, 17 Jan 2022 13:05:31 +0000 http://13.40.107.223/video/gtirnaab8kc-enhancing-in-vivo-cell-growth-with-metabolites/ Melvin Gurian, University of Twente, Enschede, The Netherlands, provides an overview of how determining the metabolic requirements for stem cell growth can accelerate the development of tissue engineered products. Certain sugars have been identified as important metabolites that can drive the growth of cells, and by creating a release system, the required amount of metabolites can sustain in vivo cell survival. This interview took place at the 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS 2021).

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