Petter Björquist – VJRegenMed

Development of personalized tissue-engineered veins

Simon Ng — Mon, 18 Oct 2021 13:59:44 +0000

Petter Björquist, PhD, VERIGRAFT, Göteborg, Sweden, provides an overview of personalized tissue-engineered veins (P-TEV), derived from donated allogeneic tissue. Donated veins are initially personalized by decellularization to reduce immunogenicity of the tissue and subsequent reconditioning enables the tissue to be transplanted into the patient without rejection by incubating the tissue in the patient’s blood and other proprietary agents. P-TEV is currently in clinical development and the technology has the potential to be applied in developing personalized nerves and urethras. This interview took place at Meeting on the Mesa 2021.

Future advancements in tissue engineering

Simon Ng — Mon, 18 Oct 2021 13:59:43 +0000

Petter Björquist, PhD, VERIGRAFT, Göteborg, Sweden, discusses some key remaining barriers in the tissue engineering. Commercialization of tissue engineered products remain a challenge, despite decellularization and reconditioning being processes that are widely known and used. Usage of stem cells additionally complicates matters from a regulatory perspective due to time, cost, and potential safety risks. Wider adoption of tissue-engineered products will require using materials such as blood which can reduce time and cost restraints. This interview took place at Meeting on the Mesa 2021.

How personalized tissue-engineered veins can overcome transplantation problems

Simon Ng — Mon, 18 Oct 2021 13:59:42 +0000

Petter Björquist, PhD, VERIGRAFT, Göteborg, Sweden, outlines issues associated with transplantation, and how personalized tissue-engineered veins (P-TEV) can overcome them. Access to donated tissue and graft rejection remain major problems in the field of transplantation and P-TEV, reconditioned blood vessels derived from donated tissue, can increase availability of available tissue suitable for donation and forego the need for immunosuppressants. This interview took place at Meeting on the Mesa 2021.