Sandra Hofmann – VJRegenMed

Creating environments for bone co-cultures

Simon Ng — Tue, 04 Jan 2022 13:03:19 +0000

Sandra Hofmann, PhD, Eindhoven University of Technology, Eindhoven, The Netherlands, discusses the applications of co-culture systems, where multiple cell types are cultured together. Co-culturing enables two different stem cells to differentiate into their respective lineages in the same media and their interactions to be studied. The interaction of co-cultured cells in a disease or normal state can additionally be assessed and Dr Hofmann additionally describes how the field can move forward in terms of tissue engineering. This interview took place at the 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS 2021).

Co-culture systems in bone research

Simon Ng — Tue, 04 Jan 2022 13:03:18 +0000

Sandra Hofmann, PhD, Eindhoven University of Technology, Eindhoven, The Netherlands, describes the role of bone co-cultures in understanding the pathophysiology of bone diseases. Recreating the cellular conditions in a healthy and diseased state can improve our understanding of how drugs interact in various environments as well as their mechanism of action. Whilst bones have regenerative potential without the need for external stimuli, further research is additionally required for the development of scaffolds in patients with larger bone fractures. This interview took place at 6th world congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS 2021).