Gynecological Cancer – VJRegenMed https://mirror.vjregenmed.com The Video Journal of Regenerative Medicine Thu, 28 Apr 2022 08:38:43 +0000 en-US hourly 1 https://wordpress.org/?v=6.5.2 https://d2xz56kaqxj8if.cloudfront.net/wp-content/uploads/2023/09/12102509/VJR-Favicon.png Gynecological Cancer – VJRegenMed https://mirror.vjregenmed.com 32 32 PiggyBac Transposon-generated CAR T-cells in solid tumors https://mirror.vjregenmed.com/video/uz1fnxol_em-piggybac-transposon-generated-car-t-cells-in-solid-tumors/ Thu, 21 Apr 2022 16:45:47 +0000 http://13.40.107.223/video/uz1fnxol_em-piggybac-transposon-generated-car-t-cells-in-solid-tumors/ Shigeki Yagyu, MD, PhD, Kyoto Prefectural University of Medicine, Kyoto, Japan, discusses the future of PiggyBac transposon-mediated chimeric antigen receptor (CAR) T-cell therapies. A clinical trial is imminently underway to assess a CAR T-cell therapy based on PiggyBac transposon technology in HER2+ bone sarcoma and gynecological cancers. Preclinical studies assessing the treatment has yielded promising results in sarcoma and brain tumors in terms of efficacy and long-term functionality. This interview took place at the International Conference on Lymphocyte Engineering (ICLE) 2022.

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