Wound Healing – VJRegenMed

Researching the impact of innervation on regenerating tissues

Simon Ng — Mon, 10 Jan 2022 15:38:55 +0000

Paul Wieringa, PhD, Maastricht University, Maastricht, The Netherlands, describes research on the impact innervation in nociceptors found in the peripheral nervous system in the context of nerve regeneration. Existing in vivo research on skin models highlights the importance of innervation on tissue function and repair in healing wounds and Dr Wieringa highlights the need for 3D in vitro models to apply this research in other tissues. This interview took place at the 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS 2021).

Photobioengineering in tissue engineering

Simon Ng — Thu, 18 Nov 2021 16:06:34 +0000

Praveen Arany, BDS, MDS, MMSc, PhD, University of Buffalo, Buffalo, NY, provides a brief overview of photobioengineering in a clinical setting, including the stimulation of certain growth factors with near-infrared irradiation in a spatiotemporal manner. Utilizing photobioengineering approaches enables controlled release of materials over a certain amount of time in a specific area. However, delivery of such approaches remain a major hurdle as various tissues and other existing materials may affect light penetration. This interview took place at the 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS 2021).

Barriers to tissue engineering research in academia

Simon Ng — Mon, 15 Nov 2021 15:14:42 +0000

Małgorzata Lewandowska-Szumieł, PhD, Medical University of Warsaw, Warsaw, Poland, discusses problems academics face in the field of tissue engineering. As tissue engineering products are classed as medicinal products, research laboratories must face increased regulations and adhere to good manufacturing practice (GMP) guidelines, increasing costs. Prof. Lewandowska-Szumieł additionally highlights the need for specialized research grants and describes her experiences in conducting clinical trials investigating adipose-derived stem cells in healing foot ulcers. This interview took place at the 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS 2021).

Healing burn wounds with biophotonics

Simon Ng — Mon, 15 Nov 2021 12:22:22 +0000

Praveen Arany, BDS, MDS, MMSc, PhD, University of Buffalo, Buffalo, NY, discusses the use of photobiomodulation (PBM) therapy in healing burn wounds. Photoactivation of latent transforming growth factor beta 1 (TGF-β1) promotes tissue regeneration in burn wounds and can inhibit inflammation, reducing susceptibility to infection. Further research is required to assess the practical application of PBM therapy, as the use of bandages in a clinical setting may affect efficacy. This interview took place at the 6th World Congress of the Tissue Engineering and Regenerative Medicine International Society (TERMIS 2021).