https://mirror.vjregenmed.com The Video Journal of Regenerative Medicine Wed, 25 Aug 2021 11:21:45 +0000 en-US hourly 1 https://wordpress.org/?v=6.5.2 https://d2xz56kaqxj8if.cloudfront.net/wp-content/uploads/2023/09/12102509/VJR-Favicon.png https://mirror.vjregenmed.com 32 32 https://mirror.vjregenmed.com/video/uexa7a74zzs-cord-blood-infusion-in-children-with-autism-spectrum-disorder/ Thu, 12 Aug 2021 18:50:03 +0000 http://13.40.107.223/video/uexa7a74zzs-cord-blood-infusion-in-children-with-autism-spectrum-disorder/ Joanne Kurtzberg, MD, Duke University, Durham, NC, describes ongoing research exploring the benefit of umbilical cord blood (UCB) infusion in children with autism spectrum disorder (ASD). An initial open-label Phase I safety study (NCT02176317) in 25 children with ASD revealed that a single infusion of autologous UCB was well tolerated. The double-blind Phase II Duke ACT trial (NCT02847182), which aimed to evaluate the efficacy of a single UCB infusion compared to placebo in 180 children with ASD, failed to meet it’s primary endpoint of improvement in the Vineland Adaptive Behavior Scales-3 (VABS-3) measure of socialization, although improvements were seen in certain patient subsets across various outcome measures. This interview took place at the 2021 World Stem Cell Summit (WSCS).

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